Question: What Does A Low IgG Subclass 1 Mean?

Can IgG deficiency be reversed?

Treatment.

Immunoglobulin deficiency diseases cannot be cured, but treatment that replaces or boosts specific immunoglobulins can help support immune function in affected children.

Treatment will also focus on controlling infections in immunodeficient children..

What kind of doctor treats IgG deficiency?

Immunologists are scientists or doctors who specialize in diseases of the immune system. Immunologist physicians may manage the treatment of patients with primary immunodeficiency disease. Infectious disease specialists are also frequently involved in the care of these patients.

What does it mean if your IgG is low?

An IgG deficiency is a health problem in which your body doesn’t make enough Immunoglobulin G (IgG). People with IgG deficiency are more likely to get infections. … These antibodies are made by B cells and plasma cells. They are let loose throughout the body to help kill bacteria, viruses, and other germs.

What are normal IgG subclass levels?

IgG Subclass Reference RangesTest/AgeIgG Subclass Reference Ranges (mg/dL)0 – 1 year20 – 851 – 3 years15 – 803 – 12 years10 – 12012 – 16 Years20 – 15023 more rows•Nov 28, 2017

What does IgG stand for?

Immunoglobulin G (IgG) is a type of antibody. Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells.

What does it mean if your IgG is high?

High levels of IgG may mean a long-term (chronic) infection, such as HIV, is present. Levels of IgG also get higher in IgG multiple myeloma, long-term hepatitis, and multiple sclerosis (MS).

Which condition is an autoimmune disease involving immunoglobulin G?

To characterize serum IgG subclass levels in several autoimmune diseases, including primary Sjogren syndrome (pSS), systemic sclerosis (SSc), systemic lupus erythematosus (SLE), and primary biliary cirrhosis (PBC).

What does IgG subclass 1 mean?

The main immunoglobulin (Ig) in human blood is IgG. … IgG is a combination of four slightly different types of IgG called IgG subclasses: IgG1, IgG2, IgG3 and IgG4. When one or more of these subclasses is persistently low and total IgG is normal, a subclass deficiency is present.

Is low IgG serious?

People with IgG deficiency are more likely to get infections. Although researchers don’t know what causes primary IgG deficiency, genetics may play a role. When the symptoms come on later in life, the health problem is harder to manage, and you may have more infections.

How is IgG deficiency treated?

Currently, the accepted therapy for IgG deficiency is the intravenous administration of 300-600 mg/kg of IgG once every 3-4 weeks, or 100-200 mg/kg/wk subcutaneously. Higher doses have been shown to be more effective in reducing infections in patients with histories of chronic or recurrent sinopulmonary infections.

How can I increase my immunoglobulin?

Eat Right Garlic. Omega-3 fatty acids, found in nuts, salmon, tuna, mackerel, and flaxseed oil. Zinc-rich foods, like oysters, crab, lean meats and poultry, and chickpeas. Selenium-rich foods, such as broccoli, sardines, tuna, brazil nuts, and barley.